ASSESSMENT OF THE GENOTOXIC EFFECTS RELATED TO CHRONIC LOW-DOSE IONISING RADIATION EXPOSURE IN POPULATION FROM BĂIȚA-ȘTEI URANIUM MINE AREA

The aim of the project is to provide data on the genetic hazards due to environmental exposure of low doses of ionizing radiation in population residing near the depleted Băița-Ştei uranium mine (Bihor County). For this purpose, two main objectives will be achieved, consisting in the accurate assessment of the annual effective dose for the population under study as well as the rigorously evaluation of the DNA damage in lymphocytes induced by radiation using the alkaline comet assay and the micronucleus test. Radiosensibility and radioprotection induced in blood cells by the exposure to low doses of ionizing radiations will be analyzed due the study of the repair kinetics. These results will provide an useful tool for government and healthcare authorities in assessing and improving the affected population health status from similar areas in Romania.

Project website: http://genorad.granturi.ubbcluj.ro/

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